In recent decades, many terrorist attacks have occurred all over the world, which have left many financial and human damages. As a result of these events, engineers felt the need to design explosion-resistant structures. Among the important structures in transportation systems are bridges. On the other hand, this important structure can be an attractive target for terrorist attacks. Therefore, the analysis and investigation of explosive loading on this structure is very important. Considering the frequency and expansion of the construction of concrete deck bridges in Iran, this research has investigated and numerically analyzed the deck slab of a reinforced concrete bridge. The parameters investigated in this research include deck displacement and deflection, stress, element removal, the amount of deck destruction and how cracks are formed, the change in scale distance and the mass of the explosive. Also, LS-DYNA finite element software has been used for modeling. The results show that on the concrete decks in the bridges, the parameters of the amount and location of the explosion are very important and effective in such a way that it causes extensive damages at the level of the near explosions. Based on the results obtained, with the increase in the weight of the explosive, the displacement and stress values in the structure increase in such a way that after the explosion of 250 kg of explosive in the air, linear cracks were created, while after the explosion of 500 kg of the explosive on On the surface of the concrete bridge deck, there is a spherical punch-like destruction with an approximate diameter of 2.4 meters. Also, by changing the explosive material from 250 kg to 500 kg TNT, the amount of displacement for the center of the bridge deck will increase by 5.5 times, and by changing the explosive material from 500 kg to 700 kg TNT, we will see an increase in the amount of displacement at the edge of the deck by 2.5 times.